Report calls for policy on extreme drug resistant TB

The report reveals that between 1997 and 2008, nearly 600 XDR-TB cases were reported from 10 tertiary care centres (referral hospitals) in nine cities.

Though TB is a bacterial disease and can be treated with antibiotics, over time many kinds of bacteria develop drug resistance. TB bacteria is especially known for this. First, there emerged multi-drug resistant (MDR) TB, which was followed by XDR-TB and now TDR-TB.

The article by researchers of Christian Medical College, Vellore, states that the treatment outcome of XDR-TB is “disappointing” as the “fatality rate is high”. In such cases, the TB bacterium would have gained resistance to Quinolone and another injectible group of drugs. The fact that there is no protocol, registry or surveillance mechanism for XDR-TB worsens the situation.

The article notes that when the organism gets transmitted to new hosts, it remains XDR. “There is an urgent need to prevent secondary transmission,” the report says.

Apparently the drug-resistant TB has a direct impact on HIV-AIDS patients too. A study that looked at the prevalence of XDR-TB in 54 HIV-infected patients found that 12 had MDR-TB and among them four had XDR-TB. All four of them died within three months of diagnosis.

Source :      2012/12/12 09:09

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