Battling infectious diseases with 3-D protein structures

The 3-D atomic structures of more than 1,000 proteins are potential targets for drugs and vaccines to combat some of the world’s most dangerous emerging and re-emerging infectious diseases, an international team of scientists has determined.
 
These experimentally determined structures have been deposited into the World-Wide Protein Data Bank, an international archive freely available to the scientific community. The 3-D structures help expedite drug and vaccine research and advance the understanding of pathogens and organisms causing infectious disease.
The University of Chicago team has recently characterized protein crystal structures with novel inhibitors from two important agents that cause human disease: Mycobacterium tuberculosis and Cryptosporidium parvium, responsible for tuberculosis and the parasitical infection cryptosporidiosis, respectively.
Source : www.sciencedaily.com      2017/7/11 11:35

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