Researchers use tiny 3D spheres to combat tuberculosis

A new 3D system has been used to study human infection in the laboratory. The team, which includes infection researchers, engineers and bioinformaticians have used an electrostatic encapsulation technique to make tiny 3D spheres within which human cells are infected with tuberculosis (TB) bacteria to generate conditions that more closely reflect events in patients.
The model allows the researchers to further investigate what happens in a human body when TB develops, with a long term aim of identifying new antibiotic treatments and vaccines. Additionally the 3D spheres are able to prolong experiments for up to three weeks, more than four times longer than standard 2D model systems. This gives researchers more information about how the infection develops and the effect of different interventions over time.
Source : www.sciencedaily.com      2017/4/9 11:51

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