New TB drug candidates developed from soil bacteria

A new treatment for TB set to be developed using compounds derived from bacterium that live in soil, according to international collaboration of researchers. A new compound – created from soil bacteria which prevent other bacteria growing around them – is an effective killer of Mycobacterium tuberculosis, which causes TB, say the scientists.
The group looked at soil bacteria compounds, known to effectively prevent other bacteria growing around them. Using synthetic chemistry, the researchers were able to recreate these compounds with structural variations, turning them into more potent chemical analogues.
When tested in a containment laboratory, these analogues proved to be effective killers of Mycobacterium tuberculosis -- the bacterium which causes TB.
Source :      2017/4/3 08:52

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