Is chemical exposure in mothers, babies, linked to linked to poor vaccine response?

Early life exposures to toxic chemicals such as PCBs and DDT dampen an infant's response to the tuberculosis vaccine, according to a new study published in the journal Lancet Respiratory Medicine. The two primary chemicals studied in the UR paper--polychlorinated biphenyls (PCBs) and DDE, the main breakdown product of the insecticide DDT--are among the world's most persistent pollutants. (Persistent pollutants are not easily degraded and thus remain a health threat long after they are banned.) Like other persistent chemicals, PCBs and DDE cross the placenta and are readily passed from mother to child through breastfeeding. Development of a robust immune system is a complex and intricate process in early life and therefore, even small changes can lead to long-term dysfunction.

Source :      2015/12/16 10:44

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