Effects of MVA85A vaccine on tuberculosis challenge in animals

A new systematic review of animal studies testing a vaccine for tuberculosis raises questions about whether the studies provided sufficient evidence to move into trials of children. The new vaccine was a virus-expressing antigen 85A (MVA85A) designed to boost the immunity offered by the existing Bacillus Calmette-Guérin (BCG) vaccine which has little protective effect in practice. The review evaluates the animal evidence that contributed to the decision to conduct human studies
Source : www.sciencedaily.com      2015/9/13 09:17

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