Determination of in vitro synergy between linezolid and other antimicrobial agents against Mycobacterium tuberculosis isolates

In a recent study, researchers explore the potential in vitro synergy between linezolid (LZD) and six other anti-TB drugs in Mycobacterium tuberculosis strains, especially multidrug-resistant tuberculosis (MDR-TB) strains. Their findings demonstrate that LZD shows the synergistic activity against both non-MDR and MDR M. tuberculosis strains when in combination with Clarithromycin, Ethambutol, Moxifloxacin, Amikacin and Clofazimine, indicating that LZD may be considered as a promising component involving the regimen for the treatment of MDR-TB.
Source : www.sciencedirect.com      2015/9/13 08:37

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