Preliminary Results of Bedaquiline as Salvage Therapy for Patients With Nontuberculous Mycobacterial Lung Disease

In a new study, Researchers describe a case series of off-label use of bedaquiline for treatment failure lung disease caused by Mycobacterium avium complex (MAC) or Mycobacterium abscessus (Mab). Bedaquiline is an oral antimycobacterial agent which is appears to be effective for the treatment of multidrug-resistant TB but has not been tested clinically for NTM disease. The small preliminary report demonstrates potential clinical and microbiologic activity of bedaquiline in patients with advanced MAC or Mab lung disease but the findings require confirmation with larger studies.
Source : journal.publications.chestnet.org      2015/8/16 13:17

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