Childhood BCG vaccination does not influence control of Mycobacterium tuberculosis growth by human bronchoalveolar lavage cells

Childhood vaccination with Mycobacterium bovis Bacille Calmette-Guérin (BCG) reduces the risk of infection with Mycobacterium tuberculosis and the risk of severe forms of tuberculosis in children. The protection of adults from pulmonary tuberculosis is doubtful. A research team from Germany evaluates the effect of the vaccination on the growth of M. tuberculosis human bronchoalveolar mononuclear cells (BALMC) in adults. The study suggests that M. bovis BCG vaccination does not alter the anti-mycobacterial capacity of BALMC as assessed in ex-vivo growth inhibition assays.
Source : www.tuberculosisjournal.com      2015/7/18 20:03

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