Xpert MTB/RIF assay for diagnosis of pulmonary tuberculosis in children: A systematic review and meta-analysis

Microbiological confirmation of childhood tuberculosis is rare because of the difficulty of collection of specimens, low sensitivity of smear microscopy, and poor access to culture. A new study aimed to establish summary estimates for sensitivity and specificity of the Xpert MTB/RIF assay compared with microscopy in the diagnosis of pulmonary tuberculosis in children. The researchers found that Xpert offers better sensitivity for the diagnosis of pulmonary tuberculosis in children and helps to provide rapid confirmation of disease.
Source : www.sciencedaily.com      2015/3/30 10:54

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