Drug-resistant TB may be treatable with new small molecule drug

In a new study, scientists report how a new small molecule drug appears able to kill drug-resistant tuberculosis without toxic side effects. They were interested in one particular molecule - an enzyme that helps to produce TB RNA called RNA polymerase, or RNAP. The compound binds to specific amino acids and magnesium in the bacterial cells and interrupts the process through which RNAP produces TB RNA. So, the TB bacterium cannot produce the proteins it needs to survive.
Source : www.medicalnewstoday.com      2015/3/14 07:51

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